Researchers show small molecules that alter RNA structure have greater functional impact than those that only bind, offering ...

The field of RNA-targeted therapeutics is rapidly evolving, offering groundbreaking opportunities for the treatment of a wide array of diseases ...

RNA transcription is the genomic process in which a cell produces a duplicate of a gene's DNA sequence. In a study published in Nucleic Acids Research, University of Alabama at Birmingham Department ...

An interdisciplinary research team from two working groups at the Center for Synthetic Biology at TU Darmstadt has developed the first RNA-based genetic switch that precisely replicates the logical ...

CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing attention as a next-generation gene therapy platform due to its precision and reduced side effects. Utilizing this system, ...

A protein called LENG8 traps defective RNA molecules inside the cell nucleus before they can reach the cytoplasm and disrupt normal cellular function, according to a study published in Molecular Cell ...

A study of a bacteria commonly used in dairy fermentation revealed how organized RNA helixes, called riboswitches, can combine different signals to keep gene expression in check. Researchers from the ...

RNA in cells performs an astounding number of functions. Messenger RNA carries the sequences of active genes to cellular machinery that turns it into proteins. And transfer RNA molecules are an ...

RNA, or ribonucleic acid, is a short-lived molecule copied from DNA that enables cells to use genetic information. Specific DNA sequences are copied into RNA, which then delivers these instructions to ...

An experimental RNA therapy from Avidity Biosciences has early clinical trial results showing it reduced by half the expression of a gene at the root of a rare, inherited form of muscular dystrophy ...