Iptacopan is an innovative, first-in-class oral small molecule that reversibly inhibits factor B—a crucial serine protease in the alternative pathway of the complement system. By targeting this point ...

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HEK293 cells were infected with AAV/E1/Neo, AAV/E2/Neo and AAV/E6/Neo, and G418 selected as described in the Material and Methods section. Each infection resulted in over 30 G418-resistant colonies, ...