Proteins are the molecular workhorses of cells. To understand their functions, scientists soon realized that they had to figure out proteins’ shapes. But solving a protein structure is a challenging ...

A team of researchers has built a new protein sequencing workflow that pairs mirror proteases with deep learning software to read peptide sequences with far greater accuracy than previous methods.

(spidroins) through long-read transcriptomics across a broad phylogenetic range, with theoretical implications for protein family evolution, biomaterials, and silk biology. By identifying putative ...

HIV-1 envelope glycoprotein (Env), a gp120–gp41 trimer, undergoes coordinated conformational changes that drive membrane fusion and allow immune evasion by transiently concealing ...

ProteomeXchange’s 2026 update shows that global proteomics data sharing continues to accelerate, with more than 64,000 ...

BACKGROUND: Despite antiplatelet therapy, some patients remain at high ischemic risk because of drug nonresponsiveness or high residual platelet reactivity). We aimed to target an orphan platelet GPCR ...

A375, HEK293T, Sk-Mel-3 and Sk-Mel-24 cell lines were obtained from the American Type Culture Collection. A375 and HEK293T cells were maintained in ...