转甲状腺素蛋白淀粉样变性（ATTR）是一类罕见的多器官损伤疾病，因体内转甲状腺素蛋白（TTR）异常折叠沉积，累及神经、心脏等关键器官，患者常面临认知低、诊疗难的困境。香港登越药业深耕罕见病创新药领域，为大家科普这款针对性创新药物——Onpattro ...

Long-term ATTR-CM trial data show durable benefits with early tafamidis or acoramidis, fewer deaths/hospitalizations, and manageable safety. This episode, titled ‘Key Efficacy and Safety ...

Life expectancy for people with ATTR amyloidosis varies, generally ranging from 3 to 15 years after symptoms appear, and depends on the specific type of the condition and any other health issues a ...

Caring for someone with ATTR amyloidosis can be physically and emotionally demanding. To reduce the chances of burnout, caregivers should also prioritize their own well-being. Factors such as ...

ATTR-CM, a stiffening of the heart that affects pumping blood, is diagnosed through tests like EKGs and MRIs. Genetic testing can help identify if ATTR-CM is hereditary or wild-type. Nuclear ...

NEW YORK – Intellia Therapeutics on Tuesday said that the US Food and Drug Administration has lifted the clinical hold on one of two trials in which the company is evaluating its in vivo CRISPR ...

Researchers conducted a retrospective cohort study using data from the US Veterans Health Administration to quantify the time from HF diagnosis to ATTR-CM diagnosis and identify predictors of delays ...

Angela Ryan Lee, MD, FACC, is a board-certified cardiology and internal medicine physician. She also holds board certifications from the American Society of Nuclear Cardiology and the National Board ...

The burgeoning field of transthyretin amyloid cardiomyopathy (ATTR-CM), which spurred excitement over a potential $20 billion market, may have just revealed the first indication of a slowdown. For the ...

Transthyretin amyloid cardiomyopathy (ATTR-CM) is a condition that makes the heart stiff and less flexible, making it harder for the heart to pump. ATTR-CM doesn't always cause symptoms. When it does, ...

Fatigue is one of the most frustrating symptoms of transthyretin cardiac amyloidosis (ATTR-CM). It can reduce your overall quality of life, limiting your ability to complete daily tasks and ...

ATTR-CM can be a life-changing diagnosis, and if you’re an older adult, it can have an especially large impact on your quality of life. Transthyretin amyloidosis cardiomyopathy (ATTR-CM) is a rare but ...