The dorsal raphe nucleus (DRN) serotonergic (5-HT) system has been implicated in regulating sleep and motor control; however, its specific role remains controversial. In this study, we found that ...

A fingernail-sized chip can now trap thousands of individual cell-shed vesicles in roughly three seconds and read their ...

Explore emerging screening technologies in drug discovery. Enhance laboratory workflows with advanced models, CRISPR, and ...

Welcome to the HADACA3-datacamp, a crowdsourced benchmarking challenge designed to advance deconvolution methods in cancer genomics. This project focuses on deconstructing cellular heterogeneity in ...

Physically magnifying objects using a key moisture-absorbing ingredient in diapers has opened an unprecedented view of the microbial world. When you slip a slide under a microscope, a system of glass ...

Microscopy is an imaging technique that enables us to see a world that would otherwise be invisible to us. Once upon a time, visualizing cells, microbes and other entities not perceptible to the naked ...

Bulk RNA sequencing (RNA-seq) has substantially advanced the understanding of pituitary neuroendocrine tumors (PitNETs). However, its limited ability to resolve cellular heterogeneity – particularly ...

A pandemic-era breakthrough has allowed scientists to literally expand our view of plankton. By using ultrastructure expansion microscopy, researchers visualized the inner workings of hundreds of ...

Welcome to the 14th Cochrane Methods report compiled by the Central Executive Team to provide an overview of the key methodological activities in Cochrane for 2024–2025. The report highlights the ...

Aim To map, summarise and analyse the methodologies of corneal nerve fibre imaging in studies using in vivo confocal microscopy (IVCM) in diabetes and assess the potential for standardising methods ...

Until today, skin, brain, and all tissues of the human body were difficult to observe in detail with an optical microscope, since the contrast in the image was hindered by the high density of their ...